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Germ Cells and Sex Determination

Module: 
2
Section: 
D

Instructor: Blanche Capel
Summary: This module will cover the formation, pluripotent characteristics, and male vs. female development of primordial germ cells in multiple species including Drosophila, C. elegans, fish and mammals. It will also cover sex determination and cell fate commitment in somatic cells of the gonad, including genetic and temperature/hormone-dependent mechanisms. We will likely also consider how sex chromosomes evolve and how species transition between sex determining mechanisms.

Readings: 

Developmental Biology, Gilbert:
Chapter 15 - Sex Determination
Chapter 17 - The Saga of the Germ Line