Joseph Heitman, Molecular Genetics & Microbiology

Our research focuses on how cells sense their environment via signal transduction cascades. Our studies center on two approaches. The first utilizes small molecules to dissect signaling cascades. The second focuses on how cells differentiate in response to nutrients. Complementary studies are conducted in the yeast Saccharomyces cerevisiae and in the opportunistic fungal pathogen Cryptococcus neoformans.