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Maki Asano, Molecular Genetics & Microbiology

My laboratory studies cell cycle regulation. This fundamental biological process is vital for homeostasis and development of every organism. Failure to accurately regulate the cell cycle leads to serious consequences including cancer, birth defects or fetal death.

To elucidate the mechanisms underlying cell cycle control, we use a combination of molecular biology, genetics, biochemistry and cell biology. As a model system, we use the fruit fly, Drosophila melanogaster. The cell cycle machinery is broadly conserved among eukaryotes, and so our experiments using the genetically tractable fruit fly will offer insight into the workings of the human cell cycle.

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