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Chay T. Kuo

George W. Brumley Associate Professor
Cell Biology
(919) 684-4612
Research Interest: 
Developmental biology
Membranes and organelles
Research Summary: 
Adult neurogenesis and how the production of new neurons in the brain is sustained and regulated.
Identification of distinct ChAT⁺ neurons and activity-dependent control of postnatal SVZ neurogenesis.
Paez-Gonzalez P, Asrican B, Rodriguez E, Kuo CT.
Nat Neurosci. 2014. 17:934-42.

Protective astrogenesis from the SVZ niche after injury is controlled by Notch modulator Thbs4.
Benner EJ, Luciano D, Jo R, Abdi K, Paez-Gonzalez P, Sheng H, Warner DS, Liu C, Eroglu C, Kuo CT.
Nature. 2013. 497:369-73.

Ank3-dependent SVZ niche assembly is required for the continued production of new neurons.
Paez-Gonzalez P, Abdi K, Luciano D, Liu Y, Soriano-Navarro M, Rawlins E, Bennett V, Garcia-Verdugo JM, Kuo CT.
Neuron. 2011. 71:61-75.