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Cell Biology of the Synapse


Instructor: Scott Soderling
Summary: How the brain is wired during development and how these connections are modified by experience are fundamental questions of neural cell biology. In this module we will cover examples of how axons navigate to properly innervate their targets. We will also cover how the synapse is formed and how the strength of the synaptic connection is modified by experience. Finally we will investigate how impairments to these processes are the basis to many neurological disorders.


Molecular Biology of the Cell, Alberts et al.
Chapter 11 - Ion Channels and the Electrical Properties of Membranes.
Chapter 21 - Neural Development.