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The Duke CMB Program has over 150 faculty members with diverse research interests in areas of Cell and Molecular Biology. CMB Program faculty have primary appointments in the Basic Science Departments of Duke Medical School and the Biological Science Departments of Duke University. The program is extremely interactive, with at least 80% of the faculty being involved in collaborations within the program.

CMB faculty are generally supported by independent research grants and awards. The faculty of over ten departments contribute to the Program, including faculty in the Clinical Sciences who have a strong focus on basic research.