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Mechanisms of Early Development


Instructor: David McClay
Summary: This module will cover the maternal to zygotic transition, initial asymmetries that launch cellular diversity, onset of signaling, mechanisms of specification, and control mechanisms necessary for morphogenesis. It will emphasize the means by which genomic information is used to drive development. Each class period will be a combination of primary literature review, lecture and discussion. Animal examples will be drawn from across the animal kingdom.


Molecular Biology of the Cell, Alberts, et al., 6th edition - Chapter 21
Developmental Biology, Gilbert, 10th edition - Chapters 1-3