Module: 
3
Section: 
A

Instructor: Kenneth Poss
Summary: Questions of how and why tissue regeneration occurs have captured the attention of countless biologists, biomedical engineers, and clinicians. Regenerative capacity differs greatly across organs and organisms, and a range of model systems that use different regenerative strategies and that offer different technical advantages have been studied to understand regeneration. In this module, we will cover key concepts and mechanisms of tissue regeneration, focusing our attention on the cellular and molecular events that drive regeneration of skeletal muscle after trauma.

Readings: 

1) Brack, A. and Rando, T. (2012). Tissue-specific stem cells: lessons from the skeletal muscle satellite cell. Cell Stem Cell 10, 504-514.
2) Poss, K. D. (2010). Advances in understanding tissue regenerative capacity and mechanisms in animals. Nature Reviews Genetics 11, 710-722.